Home / Peptides

57 profiles,
one honest library.

Every profile includes mechanism, evidence scorecard, bias-screened research log, dosing, and questions for your provider.

For educational purposes only. Profiles are not medical advice and many peptides discussed are not FDA-approved for the uses described. Consult your healthcare provider before making health decisions.

Grade key: A Strong Evidence B Emerging C Theoretical D No Human Data
C
Weight Management
5-Amino-1MQ
5-Amino-1-Methylquinolinium

5-Amino-1MQ is a small molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in cellular energy metabolism. It w…

Theoretical Read →
A
Skin & Hair
Afamelanotide
Melanotan 1 (Afamelanotide)

Afamelanotide (formerly Melanotan 1, marketed as Scenesse) is a synthetic analogue of alpha-melanocyte-stimulating hormone (alpha-MSH) that …

Strong Read →
C
Skin & Hair
AHK-Cu
AHK-Cu (Alanine-Histidine-Lysine Copper Peptide)

AHK-Cu is a copper-binding tripeptide (Ala-His-Lys-Cu) structurally related to GHK-Cu, the well-studied copper peptide. It has been investig…

Theoretical Read →
B
Weight Management
AOD-9604
Advanced Obesity Drug 9604

AOD-9604 is a modified fragment of human growth hormone (hGH fragment 177-191) that was developed by Metabolic Pharmaceuticals in Australia …

Emerging Read →
B
Immune Support
ARA-290
Cibinetide (ARA-290)

ARA-290 (cibinetide) is an 11-amino-acid peptide derived from the structure of erythropoietin (EPO) that selectively activates the innate re…

Emerging Read →
B
Recovery & Healing
BPC-157
BPC-157 (Body Protection Compound-157)

BPC-157 is a synthetic pentadecapeptide (15 amino acids) derived from a partial sequence of body protection compound found in human gastric …

Emerging Read →
A
Weight Management
Cagrilintide
Cagrilintide

Cagrilintide is a long-acting amylin analog developed by Novo Nordisk for the treatment of obesity. Amylin is a hormone co-secreted with ins…

Strong Read →
B
Cognitive & Neuro
Cerebrolysin
Cerebrolysin

Cerebrolysin is a porcine brain-derived peptide preparation consisting of low-molecular-weight neuropeptides and free amino acids. Manufactu…

Emerging Read →
B
Hormone Optimization
CJC-1295 DAC
CJC-1295 With DAC (Drug Affinity Complex)

CJC-1295 with DAC is the original formulation of CJC-1295 that includes a Drug Affinity Complex (DAC) — a maleimidopropionic acid linker tha…

Emerging Read →
C
Cognitive & Neuro
DSIP
Delta Sleep-Inducing Peptide

DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring nonapeptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) first isolated from rabbit br…

Theoretical Read →
C
Longevity & Anti-Aging
Epitalon
Epitalon (Epithalon/Epithalone)

Epitalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide based on epithalamin, a peptide extract from the pineal gland. Developed by Russian g…

Theoretical Read →
C
Longevity & Anti-Aging
FOXO4
Forkhead Box O4

FOXO4 (Forkhead Box O4) is an endogenous transcription factor, not a therapeutic peptide itself. It belongs to the FOXO family of transcript…

Theoretical Read →
D
Longevity & Anti-Aging
FOXO4-DRI
FOXO4-D-Retro-Inverso Peptide

FOXO4-DRI is a D-retro-inverso peptide designed to disrupt the interaction between FOXO4 and p53 in senescent cells. Developed by Peter de K…

No human data Read →
B
Metabolic & Body Composition
GDF-8 / Myostatin
Growth Differentiation Factor 8 (Myostatin)

GDF-8, commonly known as myostatin, is an endogenous member of the TGF-beta superfamily that acts as a negative regulator of skeletal muscle…

Emerging Read →
B
Skin & Hair
GHK-Cu
GHK-Cu (Copper Peptide GHK-Cu)

GHK-Cu is a naturally occurring copper-binding tripeptide (Gly-His-Lys) first isolated from human plasma in 1973 by Loren Pickart. It is pre…

Emerging Read →
B
Hormone Optimization
GHRP-2
GHRP-2 Acetate (Growth Hormone Releasing Peptide-2)

GHRP-2 is a synthetic hexapeptide that acts as a potent growth hormone secretagogue, stimulating the pituitary gland to release growth hormo…

Emerging Read →
B
Hormone Optimization
GHRP-6
GHRP-6 Acetate (Growth Hormone Releasing Peptide-6)

GHRP-6 is a synthetic hexapeptide and one of the earliest discovered growth hormone secretagogues. It stimulates GH release from the pituita…

Emerging Read →
A
Longevity & Anti-Aging
Glutathione
Glutathione (L-Glutathione / GSH)

Glutathione is a tripeptide (glutamate-cysteine-glycine) that is the body's most abundant and important intracellular antioxidant. It is pro…

Strong Read →
A
Hormone Optimization
HCG
HCG (Human Chorionic Gonadotropin)

Human chorionic gonadotropin (HCG) is a glycoprotein hormone naturally produced by the placenta during pregnancy. Structurally, it shares a …

Strong Read →
A
Hormone Optimization
HMG
HMG (Human Menopausal Gonadotropin)

Human menopausal gonadotropin (HMG) is a purified preparation containing both follicle-stimulating hormone (FSH) and luteinizing hormone (LH…

Strong Read →
B
Metabolic & Body Composition
IGF-1 LR3
IGF-1 LR3 (Long Arginine 3 Insulin-like Growth Factor-1)

IGF-1 LR3 is a synthetic, modified version of insulin-like growth factor-1 (IGF-1). The modification — substitution of arginine at position …

Emerging Read →
B
Hormone Optimization
Ipamorelin
Ipamorelin Acetate

Ipamorelin is a synthetic pentapeptide growth hormone secretagogue that selectively stimulates GH release from the pituitary gland. It is co…

Emerging Read →
B
Hormone Optimization
Kisspeptin-10
Kisspeptin-10

Kisspeptin-10 is the biologically active decapeptide fragment of the kisspeptin family, which are endogenous neuropeptides encoded by the KI…

Emerging Read →
C
Gut & Inflammation
KPV
KPV (Lys-Pro-Val, alpha-MSH Fragment 11-13)

KPV is a naturally occurring tripeptide (Lysine-Proline-Valine) derived from the C-terminal end of alpha-melanocyte-stimulating hormone (alp…

Theoretical Read →
A
Metabolic & Body Composition
L-Carnitine
L-Carnitine

L-Carnitine is a naturally occurring amino acid derivative synthesized from lysine and methionine, primarily in the liver and kidneys. Its p…

Strong Read →
B
Weight Management
Lipo-C
Lipo-C (Lipotropic Injection)

Lipo-C is a compounded lipotropic injection containing a combination of methionine, inositol, choline (MIC), and typically vitamin B12 (cyan…

Emerging Read →
B
Immune Support
LL-37
LL-37 (Human Cathelicidin Antimicrobial Peptide)

LL-37 is the only cathelicidin-derived antimicrobial peptide found in humans. It is a 37-amino-acid peptide (beginning with two leucines, he…

Emerging Read →
B
Weight Management
Mazdutide
Mazdutide (LY3305677 / IBI362)

Mazdutide is a novel dual GLP-1 and glucagon receptor agonist developed by Innovent Biologics (in partnership with Eli Lilly). It is designe…

Emerging Read →
B
Sexual Health
Melanotan 2
Melanotan II

Melanotan II is a synthetic cyclic peptide analogue of alpha-melanocyte-stimulating hormone (alpha-MSH) that acts as a non-selective melanoc…

Emerging Read →
A
Longevity & Anti-Aging
Melatonin
Melatonin (N-acetyl-5-methoxytryptamine)

Melatonin is an endogenous hormone produced primarily by the pineal gland in response to darkness, serving as the body's master circadian rh…

Strong Read →
B
Hormone Optimization
Mod GRF 1-29
CJC-1295 Without DAC (Modified GRF 1-29)

CJC-1295 without DAC, also known as Modified GRF (1-29) or tesamorelin-related analog, is a synthetic analog of growth hormone-releasing hor…

Emerging Read →
B
Longevity & Anti-Aging
MOTS-c
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-c)

MOTS-c is a mitochondrial-derived peptide (MDP) encoded within the 12S rRNA gene of the mitochondrial genome. Discovered in 2015 by Changhan…

Emerging Read →
B
Longevity & Anti-Aging
NAD+
NAD+ (Nicotinamide Adenine Dinucleotide)

NAD+ is a critical coenzyme found in every living cell, essential for hundreds of metabolic reactions including energy production, DNA repai…

Emerging Read →
A
Hormone Optimization
Oxytocin
Oxytocin

Oxytocin is a nine-amino-acid neuropeptide produced in the hypothalamus and released by the posterior pituitary gland. Often called the 'bon…

Strong Read →
D
Cognitive & Neuro
P21
P21 (CNTF-Derived Peptide)

P21 is a small synthetic peptide derived from the active region of ciliary neurotrophic factor (CNTF). It was designed to mimic CNTF's neuro…

No human data Read →
D
Cognitive & Neuro
PE-22-28
PE-22-28 (Spadin Analogue)

PE-22-28 is a synthetic peptide derived from spadin, a natural peptide that inhibits the TREK-1 potassium channel. TREK-1 inhibition has bee…

No human data Read →
C
Recovery & Healing
PEG-MGF
PEG-MGF (PEGylated Mechano Growth Factor)

PEG-MGF is a PEGylated (polyethylene glycol-modified) form of mechano growth factor, a splice variant of IGF-1 (insulin-like growth factor 1…

Theoretical Read →
C
Cognitive & Neuro
Pinealon
Pinealon (EDR Peptide)

Pinealon is a synthetic tripeptide (Glu-Asp-Arg, or EDR) developed by Russian gerontologist Vladimir Khavinson as part of his bioregulatory …

Theoretical Read →
A
Sexual Health
PT-141 / Bremelanotide
PT-141 (Bremelanotide)

Bremelanotide (brand name Vyleesi) is a melanocortin receptor agonist FDA-approved in June 2019 for the treatment of hypoactive sexual desir…

Strong Read →
B
Cognitive & Neuro
Selank
Selank (TP-7)

Selank is a synthetic peptide developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. It is a synthetic analogu…

Emerging Read →
A
Weight Management
Semaglutide
Semaglutide (Ozempic / Wegovy / Rybelsus)

Semaglutide is a GLP-1 receptor agonist approved by the FDA in multiple formulations: Ozempic (injectable, T2D), Wegovy (injectable, obesity…

Strong Read →
B
Cognitive & Neuro
Semax
Semax (ACTH 4-10 Analogue)

Semax is a synthetic peptide analogue of ACTH (adrenocorticotropic hormone) fragment 4-10 with an added Pro-Gly-Pro C-terminal tripeptide fo…

Emerging Read →
A
Hormone Optimization
Sermorelin
Sermorelin Acetate

Sermorelin is a synthetic peptide consisting of the first 29 amino acids of the 44-amino-acid growth hormone-releasing hormone (GHRH). It wa…

Strong Read →
D
Metabolic & Body Composition
SLU-PP-332
SLU-PP-332

SLU-PP-332 is a small molecule agonist of estrogen-related receptors (ERRs), particularly ERRalpha, ERRbeta, and ERRgamma. Developed at Wash…

No human data Read →
C
Skin & Hair
SNAP-8
Acetyl Octapeptide-3 (SNAP-8)

SNAP-8 is a synthetic octapeptide cosmetic ingredient designed to reduce the appearance of expression lines and wrinkles by modulating neuro…

Theoretical Read →
B
Longevity & Anti-Aging
SS-31
Elamipretide (SS-31)

SS-31 (Elamipretide) is a mitochondria-targeted tetrapeptide that selectively concentrates in the inner mitochondrial membrane where it inte…

Emerging Read →
B
Weight Management
Survodutide
Survodutide (BI 456906)

Survodutide is an investigational dual agonist of the glucagon-like peptide-1 (GLP-1) receptor and the glucagon receptor, developed by Boehr…

Emerging Read →
B
Recovery & Healing
TB-500
TB-500 (Thymosin Beta-4 Fragment)

TB-500 is a synthetic peptide fragment corresponding to amino acids 17–23 of Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino acid prot…

Emerging Read →
A
Hormone Optimization
Tesamorelin
Tesamorelin (Egrifta)

Tesamorelin is a synthetic analog of growth hormone-releasing hormone (GHRH) that is FDA-approved for the treatment of HIV-associated lipody…

Strong Read →
D
Longevity & Anti-Aging
Testagen
Testagen (Khavinson Tetrapeptide)

Testagen is a synthetic tetrapeptide bioregulator (Lys-Glu-Asp-Gly) developed by Russian researcher Vladimir Khavinson, purported to act on …

No human data Read →
B
Immune Support
Thymalin
Thymalin (Thymic Bioregulator Peptide Complex)

Thymalin is a polypeptide complex extracted from bovine thymus gland tissue, developed by Vladimir Khavinson and colleagues in the Soviet Un…

Emerging Read →
A
Immune Support
Thymosin Alpha-1
Thymosin Alpha-1 (Zadaxin)

Thymosin Alpha-1 (Tα1) is a 28-amino acid peptide originally isolated from thymosin fraction 5 of bovine thymus by Allan Goldstein in the 19…

Strong Read →
A
Weight Management
Tirzepatide
Tirzepatide (Mounjaro / Zepbound)

Tirzepatide is a once-weekly injectable dual agonist of the glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like pe…

Strong Read →
D
Immune Support
Vilon
Vilon (Lys-Glu Dipeptide Bioregulator)

Vilon is a synthetic dipeptide (Lys-Glu) developed by Vladimir Khavinson as a bioregulator peptide purported to derive from bone marrow and …

No human data Read →
B
Gut & Inflammation
VIP
Vasoactive Intestinal Peptide (VIP)

Vasoactive Intestinal Peptide (VIP) is a 28-amino acid neuropeptide naturally produced throughout the nervous system, gut, and immune tissue…

Emerging Read →
B
Weight Management
Retatrutide
Retatrutide (LY3437943)

Retatrutide is an investigational once-weekly injectable triple agonist of the glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotr…

Emerging Read →
D
Cognitive & Neuro
Brenipatide
Brenipatide (LY3537031)

Brenipatide (development code LY3537031, also referenced in earlier materials as LY3843513) is an investigational once-monthly, long-acting …

No human data Read →
Often underrepresented

Peptides for women.

The peptide space is overwhelmingly male-oriented. Here are profiles with research specifically relevant to women's health goals.

5-Amino-1MQ

NNMT expression varies between sexes and may play different metabolic roles in women. No sex-specific clinical data exis…

Afamelanotide

EPP affects men and women equally. Afamelanotide is contraindicated in pregnancy due to insufficient data. Women of chil…

AHK-Cu

Female pattern hair loss (androgenetic alopecia) affects up to 50% of women. Copper peptides including AHK-Cu have been …

AOD-9604

AOD-9604 clinical trials included women. Its GH-fragment mechanism avoids androgenic effects, making it potentially suit…

ARA-290

Sarcoidosis affects women disproportionately, and small fiber neuropathy is more prevalent in women. Clinical trials of …

BPC-157

Women with musculoskeletal injuries, IBD, or post-surgical healing needs represent a large portion of potential BPC-157 …

Cagrilintide

Clinical trials included substantial female enrollment. Weight management considerations differ for women regarding repr…

Cerebrolysin

Stroke risk increases significantly in women post-menopause. Clinical trials included female participants. No sex-specif…

CJC-1295 DAC

Same considerations as CJC-1295 no-DAC. The sustained GH elevation from the DAC version may have more pronounced effects…

DSIP

Women are disproportionately affected by insomnia, particularly during perimenopause and menopause. DSIP's effects on co…

Epitalon

Melatonin regulation is relevant for women's health, particularly during perimenopause when circadian disruption is comm…

FOXO4-DRI

Cellular senescence contributes to reproductive aging and ovarian decline. Senolytic approaches are being explored for a…

GDF-8 / Myostatin

Sarcopenia disproportionately affects postmenopausal women due to estrogen decline. Myostatin levels may be hormonally r…

GHK-Cu

GHK-Cu is particularly relevant for women given its applications in cosmetic skin aging and female-pattern hair loss (an…

GHRP-2

GHRP-2 has been studied in both men and women. Women tend to have a higher baseline GH secretion and may respond differe…

GHRP-6

GHRP-6 has been studied in women with results comparable to men for GH stimulation. The strong appetite-stimulating effe…

Glutathione

Glutathione is widely used by women for skin brightening, anti-aging, and immune support. It has been studied for reduci…

HCG

HCG is a cornerstone of female fertility treatment, used to trigger ovulation in IVF and IUI protocols. It is the hormon…

HMG

HMG is a primary tool in female fertility treatment and IVF protocols. Women should be closely monitored during treatmen…

IGF-1 LR3

IGF-1 LR3 affects women similarly to men. Women should be particularly aware of the hypoglycemia risk. There is no data …

Ipamorelin

Ipamorelin is widely used by women in anti-aging and optimization protocols. Its clean side effect profile (no significa…

Kisspeptin-10

Kisspeptin is highly relevant for women, particularly in reproductive medicine. It is being studied as a safer alternati…

KPV

KPV is equally relevant for women, particularly for gut inflammatory conditions, which disproportionately affect women. …

L-Carnitine

L-Carnitine is relevant for women in several contexts: it has been studied for PCOS-related metabolic dysfunction, impro…

Lipo-C

Lipo-C injections are frequently used by women in weight management programs. The inositol component has specific eviden…

LL-37

LL-37 is equally relevant for women. It plays a role in female reproductive tract defense and has been studied in the co…

Mazdutide

Mazdutide is relevant for women with obesity and metabolic syndrome. As with other GLP-1 class drugs, women of reproduct…

Melanotan 2

Melanotan II has shown sexual arousal effects in women in early research, which led to the development of bremelanotide …

Melatonin

Melatonin is highly relevant for women. It plays a role in regulating reproductive hormone secretion and has been studie…

Mod GRF 1-29

Women naturally have higher GH pulse frequency than men. GH secretagogues may have different dose-response profiles in w…

MOTS-c

MOTS-c levels have been shown to decline with age in both sexes. Metabolic syndrome, insulin resistance, and age-related…

NAD+

NAD+ decline affects both sexes. Some research suggests NAD+ may be particularly relevant for women's reproductive aging…

Oxytocin

Oxytocin is profoundly relevant for women's health. It is critical for labor, breastfeeding, and maternal bonding. Women…

P21

Alzheimer's disease disproportionately affects women, who represent approximately two-thirds of cases. If P21 advances t…

PE-22-28

Depression affects women at approximately twice the rate of men. If TREK-1-targeted therapies advance to human trials, t…

PEG-MGF

Sarcopenia and age-related muscle loss affect women significantly, particularly post-menopause when declining estrogen a…

Pinealon

Cognitive decline and neurodegeneration affect women disproportionately. Pinealon's proposed effects on circadian rhythm…

PT-141 / Bremelanotide

Bremelanotide was specifically developed and approved for women with HSDD. It represents a milestone as the first on-dem…

Selank

Anxiety disorders are approximately twice as common in women as in men. Selank's anxiolytic effects without the sedation…

Semaglutide

Semaglutide is highly relevant for women. PCOS, which affects 10–15% of reproductive-age women, involves insulin resista…

Semax

Stroke is a leading cause of death in women and cognitive decline disproportionately affects women. Semax's neuroprotect…

Sermorelin

GH decline affects both sexes with aging. Women may respond differently to GH secretagogues due to estrogen's modulating…

SLU-PP-332

Despite the name 'estrogen-related receptors,' ERRs do not bind estrogen and are distinct from estrogen receptors. SLU-P…

SNAP-8

SNAP-8 is marketed primarily to women given gender-based cosmetic marketing norms. No sex-specific biological difference…

SS-31

Women with Barth syndrome are extremely rare (X-linked, primarily affects males). However, mitochondrial dysfunction in …

Survodutide

Women represent a large proportion of NASH and obesity patients and were well-represented in phase II trials. Hormonal f…

Thymosin Alpha-1

Thymosin Alpha-1 is relevant for women with chronic viral hepatitis, autoimmune-mediated conditions, and cancer where im…

Tirzepatide

Tirzepatide is highly relevant for women, who bear disproportionate burden of obesity-related metabolic conditions. Clin…

VIP

CIRS and mold illness disproportionately affect women in published patient populations, and women are more commonly diag…

Retatrutide

Phase 2 trials enrolled substantial proportions of women. As with other incretin agents, delayed gastric emptying may re…

Brenipatide

AUD in women carries distinct clinical features — faster progression of alcohol-related organ injury and higher rates of…