💪 15 peptides · sorted by evidence

Peptides for hormone optimization.

Growth hormone secretagogues and peptides studied for hormonal balance and optimization.

Educational content only

Inclusion in this category means the peptide is being researched for this purpose — not that it's proven effective. Always consult your healthcare provider.

Strong Evidence Sexual Health

HCG

Human chorionic gonadotropin (HCG) is a glycoprotein hormone naturally produced by the placenta during pregnancy. Structurally, it shares a common alpha subunit...

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Strong Evidence Sexual Health

HMG

Human menopausal gonadotropin (HMG) is a purified preparation containing both follicle-stimulating hormone (FSH) and luteinizing hormone (LH) activity, original...

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Strong Evidence Cognitive & Neuro

Oxytocin

Oxytocin is a nine-amino-acid neuropeptide produced in the hypothalamus and released by the posterior pituitary gland. Often called the 'bonding hormone,' it pl...

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Strong Evidence Sexual Health

PT-141 / Bremelanotide

Bremelanotide (brand name Vyleesi) is a melanocortin receptor agonist FDA-approved in June 2019 for the treatment of hypoactive sexual desire disorder (HSDD) in...

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Strong Evidence Longevity & Anti-Aging

Sermorelin

Sermorelin is a synthetic peptide consisting of the first 29 amino acids of the 44-amino-acid growth hormone-releasing hormone (GHRH). It was FDA-approved in 19...

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Strong Evidence Metabolic & Body Composition

Tesamorelin

Tesamorelin is a synthetic analog of growth hormone-releasing hormone (GHRH) that is FDA-approved for the treatment of HIV-associated lipodystrophy (excess abdo...

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Emerging Longevity & Anti-AgingMetabolic & Body Composition

CJC-1295 DAC

CJC-1295 with DAC is the original formulation of CJC-1295 that includes a Drug Affinity Complex (DAC) — a maleimidopropionic acid linker that covalently binds t...

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Emerging Metabolic & Body Composition

GHRP-2

GHRP-2 is a synthetic hexapeptide that acts as a potent growth hormone secretagogue, stimulating the pituitary gland to release growth hormone. It binds to the ...

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Emerging Metabolic & Body Composition

GHRP-6

GHRP-6 is a synthetic hexapeptide and one of the earliest discovered growth hormone secretagogues. It stimulates GH release from the pituitary by activating the...

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Emerging Metabolic & Body Composition

IGF-1 LR3

IGF-1 LR3 is a synthetic, modified version of insulin-like growth factor-1 (IGF-1). The modification — substitution of arginine at position 3 and extension of t...

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Emerging Longevity & Anti-AgingRecovery & Healing

Ipamorelin

Ipamorelin is a synthetic pentapeptide growth hormone secretagogue that selectively stimulates GH release from the pituitary gland. It is considered the most se...

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Emerging Sexual Health

Kisspeptin-10

Kisspeptin-10 is the biologically active decapeptide fragment of the kisspeptin family, which are endogenous neuropeptides encoded by the KISS1 gene. Kisspeptin...

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Emerging Longevity & Anti-AgingMetabolic & Body Composition

Mod GRF 1-29

CJC-1295 without DAC, also known as Modified GRF (1-29) or tesamorelin-related analog, is a synthetic analog of growth hormone-releasing hormone (GHRH) with fou...

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Theoretical Cognitive & Neuro

DSIP

DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring nonapeptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) first isolated from rabbit brain in 1977. It was ...

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No Human Data Longevity & Anti-Aging

Testagen

Testagen is a synthetic tetrapeptide bioregulator (Lys-Glu-Asp-Gly) developed by Russian researcher Vladimir Khavinson, purported to act on gonadal tissue and s...

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Clinician conversation

Questions to ask your doctor about hormone optimization.

  1. 01 What peptides, if any, have evidence for my specific hormone optimization goals?
  2. 02 What lab work should I have done before and during any peptide therapy?
  3. 03 How would this interact with my current medications or health conditions?
  4. 04 What's a realistic timeline for results based on the current research?
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