🧬 23 peptides · sorted by evidence

Peptides for longevity & anti-aging.

Peptides being researched for cellular repair, telomere support, and healthy aging.

Educational content only

Inclusion in this category means the peptide is being researched for this purpose — not that it's proven effective. Always consult your healthcare provider.

Strong Evidence Immune SupportSkin & Hair

Glutathione

Glutathione is a tripeptide (glutamate-cysteine-glycine) that is the body's most abundant and important intracellular antioxidant. It is produced naturally in e...

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Strong Evidence Cognitive & NeuroImmune Support

Melatonin

Melatonin is an endogenous hormone produced primarily by the pineal gland in response to darkness, serving as the body's master circadian rhythm regulator. It i...

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Strong Evidence Weight ManagementMetabolic & Body Composition

Semaglutide

Semaglutide is a GLP-1 receptor agonist approved by the FDA in multiple formulations: Ozempic (injectable, T2D), Wegovy (injectable, obesity), and Rybelsus (ora...

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Strong Evidence Hormone Optimization

Sermorelin

Sermorelin is a synthetic peptide consisting of the first 29 amino acids of the 44-amino-acid growth hormone-releasing hormone (GHRH). It was FDA-approved in 19...

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Strong Evidence Immune Support

Thymosin Alpha-1

Thymosin Alpha-1 (Tα1) is a 28-amino acid peptide originally isolated from thymosin fraction 5 of bovine thymus by Allan Goldstein in the 1970s. The synthetic v...

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Emerging Hormone OptimizationMetabolic & Body Composition

CJC-1295 DAC

CJC-1295 with DAC is the original formulation of CJC-1295 that includes a Drug Affinity Complex (DAC) — a maleimidopropionic acid linker that covalently binds t...

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Emerging Skin & HairRecovery & Healing

GHK-Cu

GHK-Cu is a naturally occurring copper-binding tripeptide (Gly-His-Lys) first isolated from human plasma in 1973 by Loren Pickart. It is present in blood, saliv...

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Emerging Hormone OptimizationRecovery & Healing

Ipamorelin

Ipamorelin is a synthetic pentapeptide growth hormone secretagogue that selectively stimulates GH release from the pituitary gland. It is considered the most se...

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Emerging Hormone OptimizationMetabolic & Body Composition

Mod GRF 1-29

CJC-1295 without DAC, also known as Modified GRF (1-29) or tesamorelin-related analog, is a synthetic analog of growth hormone-releasing hormone (GHRH) with fou...

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Emerging Metabolic & Body Composition

MOTS-c

MOTS-c is a mitochondrial-derived peptide (MDP) encoded within the 12S rRNA gene of the mitochondrial genome. Discovered in 2015 by Changhan Lee's lab at USC, i...

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Emerging Metabolic & Body Composition

NAD+

NAD+ is a critical coenzyme found in every living cell, essential for hundreds of metabolic reactions including energy production, DNA repair, and sirtuin activ...

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Emerging Recovery & Healing

SS-31

SS-31 (Elamipretide) is a mitochondria-targeted tetrapeptide that selectively concentrates in the inner mitochondrial membrane where it interacts with cardiolip...

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Emerging Recovery & Healing

TB-500

TB-500 is a synthetic peptide fragment corresponding to amino acids 17–23 of Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino acid protein found in high co...

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Emerging Immune Support

Thymalin

Thymalin is a polypeptide complex extracted from bovine thymus gland tissue, developed by Vladimir Khavinson and colleagues in the Soviet Union/Russia. It is us...

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Theoretical Immune Support

Epitalon

Epitalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide based on epithalamin, a peptide extract from the pineal gland. Developed by Russian gerontologist Vladimi...

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Theoretical

FOXO4

FOXO4 (Forkhead Box O4) is an endogenous transcription factor, not a therapeutic peptide itself. It belongs to the FOXO family of transcription factors that reg...

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Theoretical Cognitive & Neuro

Pinealon

Pinealon is a synthetic tripeptide (Glu-Asp-Arg, or EDR) developed by Russian gerontologist Vladimir Khavinson as part of his bioregulatory peptide program. It ...

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Theoretical Skin & Hair

SNAP-8

SNAP-8 is a synthetic octapeptide cosmetic ingredient designed to reduce the appearance of expression lines and wrinkles by modulating neuromuscular signal tran...

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No Human Data Recovery & Healing

FOXO4-DRI

FOXO4-DRI is a D-retro-inverso peptide designed to disrupt the interaction between FOXO4 and p53 in senescent cells. Developed by Peter de Keizer's lab at Erasm...

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No Human Data Cognitive & Neuro

P21

P21 is a small synthetic peptide derived from the active region of ciliary neurotrophic factor (CNTF). It was designed to mimic CNTF's neurotrophic effects whil...

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No Human Data Metabolic & Body Composition

SLU-PP-332

SLU-PP-332 is a small molecule agonist of estrogen-related receptors (ERRs), particularly ERRalpha, ERRbeta, and ERRgamma. Developed at Washington University in...

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No Human Data Hormone Optimization

Testagen

Testagen is a synthetic tetrapeptide bioregulator (Lys-Glu-Asp-Gly) developed by Russian researcher Vladimir Khavinson, purported to act on gonadal tissue and s...

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No Human Data Immune Support

Vilon

Vilon is a synthetic dipeptide (Lys-Glu) developed by Vladimir Khavinson as a bioregulator peptide purported to derive from bone marrow and modulate immune func...

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Clinician conversation

Questions to ask your doctor about longevity & anti-aging.

  1. 01 What peptides, if any, have evidence for my specific longevity & anti-aging goals?
  2. 02 What lab work should I have done before and during any peptide therapy?
  3. 03 How would this interact with my current medications or health conditions?
  4. 04 What's a realistic timeline for results based on the current research?
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