🔥 22 peptides · sorted by evidence

Peptides for metabolic & body composition.

Peptides studied for metabolic function, fat metabolism, and body composition.

Educational content only

Inclusion in this category means the peptide is being researched for this purpose — not that it's proven effective. Always consult your healthcare provider.

Strong Evidence Weight Management

Cagrilintide

Cagrilintide is a long-acting amylin analog developed by Novo Nordisk for the treatment of obesity. Amylin is a hormone co-secreted with insulin from pancreatic...

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Strong Evidence Recovery & HealingCognitive & Neuro

L-Carnitine

L-Carnitine is a naturally occurring amino acid derivative synthesized from lysine and methionine, primarily in the liver and kidneys. Its primary biological ro...

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Strong Evidence Weight ManagementLongevity & Anti-Aging

Semaglutide

Semaglutide is a GLP-1 receptor agonist approved by the FDA in multiple formulations: Ozempic (injectable, T2D), Wegovy (injectable, obesity), and Rybelsus (ora...

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Strong Evidence Hormone Optimization

Tesamorelin

Tesamorelin is a synthetic analog of growth hormone-releasing hormone (GHRH) that is FDA-approved for the treatment of HIV-associated lipodystrophy (excess abdo...

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Strong Evidence Weight Management

Tirzepatide

Tirzepatide is a once-weekly injectable dual agonist of the glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) rece...

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Emerging Weight Management

AOD-9604

AOD-9604 is a modified fragment of human growth hormone (hGH fragment 177-191) that was developed by Metabolic Pharmaceuticals in Australia as an anti-obesity a...

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Emerging Hormone OptimizationLongevity & Anti-Aging

CJC-1295 DAC

CJC-1295 with DAC is the original formulation of CJC-1295 that includes a Drug Affinity Complex (DAC) — a maleimidopropionic acid linker that covalently binds t...

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Emerging Recovery & Healing

GDF-8 / Myostatin

GDF-8, commonly known as myostatin, is an endogenous member of the TGF-beta superfamily that acts as a negative regulator of skeletal muscle growth. Rather than...

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Emerging Hormone Optimization

GHRP-2

GHRP-2 is a synthetic hexapeptide that acts as a potent growth hormone secretagogue, stimulating the pituitary gland to release growth hormone. It binds to the ...

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Emerging Hormone Optimization

GHRP-6

GHRP-6 is a synthetic hexapeptide and one of the earliest discovered growth hormone secretagogues. It stimulates GH release from the pituitary by activating the...

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Emerging Hormone Optimization

IGF-1 LR3

IGF-1 LR3 is a synthetic, modified version of insulin-like growth factor-1 (IGF-1). The modification — substitution of arginine at position 3 and extension of t...

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Emerging Weight Management

Lipo-C

Lipo-C is a compounded lipotropic injection containing a combination of methionine, inositol, choline (MIC), and typically vitamin B12 (cyanocobalamin or methyl...

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Emerging Weight Management

Mazdutide

Mazdutide is a novel dual GLP-1 and glucagon receptor agonist developed by Innovent Biologics (in partnership with Eli Lilly). It is designed to combine the app...

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Emerging Hormone OptimizationLongevity & Anti-Aging

Mod GRF 1-29

CJC-1295 without DAC, also known as Modified GRF (1-29) or tesamorelin-related analog, is a synthetic analog of growth hormone-releasing hormone (GHRH) with fou...

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Emerging Longevity & Anti-Aging

MOTS-c

MOTS-c is a mitochondrial-derived peptide (MDP) encoded within the 12S rRNA gene of the mitochondrial genome. Discovered in 2015 by Changhan Lee's lab at USC, i...

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Emerging Longevity & Anti-Aging

NAD+

NAD+ is a critical coenzyme found in every living cell, essential for hundreds of metabolic reactions including energy production, DNA repair, and sirtuin activ...

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Emerging Weight Management

Survodutide

Survodutide is an investigational dual agonist of the glucagon-like peptide-1 (GLP-1) receptor and the glucagon receptor, developed by Boehringer Ingelheim. It ...

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Emerging Weight Management

Retatrutide

Retatrutide is an investigational once-weekly injectable triple agonist of the glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GI...

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Theoretical Weight Management

5-Amino-1MQ

5-Amino-1MQ is a small molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in cellular energy metabolism. It was developed as a re...

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Theoretical Recovery & Healing

PEG-MGF

PEG-MGF is a PEGylated (polyethylene glycol-modified) form of mechano growth factor, a splice variant of IGF-1 (insulin-like growth factor 1) that is produced i...

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No Human Data Longevity & Anti-Aging

SLU-PP-332

SLU-PP-332 is a small molecule agonist of estrogen-related receptors (ERRs), particularly ERRalpha, ERRbeta, and ERRgamma. Developed at Washington University in...

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No Human Data Cognitive & Neuro

Brenipatide

Brenipatide (development code LY3537031, also referenced in earlier materials as LY3843513) is an investigational once-monthly, long-acting dual GLP-1 / GIP rec...

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Clinician conversation

Questions to ask your doctor about metabolic & body composition.

  1. 01 What peptides, if any, have evidence for my specific metabolic & body composition goals?
  2. 02 What lab work should I have done before and during any peptide therapy?
  3. 03 How would this interact with my current medications or health conditions?
  4. 04 What's a realistic timeline for results based on the current research?
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